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Acupuncture may protect against the development of depression in patients with primary dysmenorrhea. This study provides insight into the potential molecular mechanisms underlying the therapeutic effects of acupuncture in primary dysmenorrhea management and depression prevention.
The risk of developing depression was reduced by 64 % in acupuncture users compared with non-acupuncture users during the 19-year follow-up period. The decrease was dose-dependent.
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J Affect Disord. 2023;344:48-60. doi:10.1016/j.jad.2023.10.013
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