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Effect of acupuncture on pain and substance P levels in middle-aged women with chronic neck pain - Evidence Based Acupuncture


There was an improvement in both visual analogue scale (VAS) and neck disability index (NDI) after 4 weeks treatment. Substance P (SP) level was decreased after 4 weeks treatment.

We could conclude that acupuncture is effective in alleviating chronic neck pain. Moreover, our findings revealed the efficacy of acupuncture on chronic pain with potential underlying biological mechanisms.

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Front Neurol. 2023;14:1267952. Published 2023 Oct 19. doi:10.3389/fneur.2023.1267952

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